Researchers at the MRC Laboratory of Medical Sciences (LMS) and collaborators have uncovered one of the earliest steps in DNA replication: the moment a cell first opens its DNA to begin making a copy ...

A new discovery by researchers at the RIKEN Center for Biosystems Dynamics (BDR) in Japan upends decades of assumptions regarding DNA replication. Led by Ichiro Hiratani and colleagues, the ...

Before a cell can divide, it has to precisely duplicate its entire genetic information. However, the DNA in the cell exists as part of a DNA-protein complex known as chromatin. For this purpose, the ...

Cells have evolved careful checks to ensure DNA is copied only once, but how they switch on replication at the right moment has been the focus of a 30-year research question. New work from the Crick ...

DNA replication and repair mechanisms constitute the foundation of genomic integrity, ensuring that genetic information is faithfully duplicated and maintained across cell generations. Replication ...

This voice experience is generated by AI. Learn more. This voice experience is generated by AI. Learn more. DNA doesn’t just carry information in its sequence; fleeting alternative folds like i‑DNA ...

Johns Hopkins Kimmel Cancer Center scientists report data from a new study providing evidence that random, unpredictable DNA copying "mistakes" account for nearly two-thirds of the mutations that ...

Nearly every cell in your body contains the exact same DNA, from your skin cells to your brain cells. But how does a cell know how and when to turn into skin, muscle or brain? Imagine that the DNA in ...

A new review proposes that the DNA damage response drives PD-L1 upregulation in senescent cells, enabling immune evasion and ...